Recently, with the increasingly fierce market competition in the packaging industry, the optimization of regional layout has become a core measure for the industry to improve service capabilities and seize development opportunities. At present, the packaging industry has gradually moved away from the decentralized layout model and gathered towards core economic circles, forming a large-scale and efficient industrial pattern. Among them, the Yangtze River Delta and Pearl River Delta economic circles have become key layout areas, leading the upgrading of service efficiency in the industry. To quickly respond to market changes and improve the convenience of customer service, enterprises in the industry have successively laid out production factories and warehousing bases in the two core regions of the Yangtze River Delta and Pearl River Delta, building an efficient production and distribution network covering East China and South China. According to industry observations, leading enterprises generally have multiple production factories and warehousing bases with a considerable total area. This move not only effectively shortens the product delivery cycle and reduces logistics costs, but also accurately meets the packaging needs of downstream industries such as clothing and e-commerce in the two regions, provides more timely customized services, and promotes the transformation of the packaging industry towards efficiency and refinement.